India has recorded a total of 1,010 active COVID-19 cases as of May 27, 2025, according to the Union Health Ministry. The increase comes alongside the emergence of two new sub-variants — NB.1.8.1 and LF.7 — which are currently under global observation.
Kerala continues to be the most affected state, reporting 335 new cases, raising its active caseload to 430. Maharashtra followed with 153 fresh infections, taking its active tally to 209. Delhi, with 99 new cases, now has 104 active cases, with 24 recoveries reported over the past week.
Other states showing a noticeable rise include Gujarat (83 cases), Karnataka (47), Uttar Pradesh (15), and West Bengal (12). In Karnataka, most of the new cases — 35 out of 37 — were recorded in Bengaluru, with the state’s active caseload reaching 80 and a 24-hour positivity rate of 19.37%.
Genome sequencing conducted by the Indian SARS-CoV-2 Genomics Consortium (INSACOG) confirmed the presence of the NB.1.8.1 and LF.7 variants. These have been designated as Variants Under Monitoring (VUM) by the World Health Organization, meaning they are not currently classified as Variants of Concern but are being closely watched.
A sample from Tamil Nadu was among those found to carry the NB.1.8.1 subvariant and has been sent for further sequencing. While the national caseload remains relatively low, health experts are urging caution, noting similar upward trends in infections internationally.
In light of the increase, the Union Health Secretary held a nationwide review meeting on Saturday to assess the COVID-19 situation and ensure preparedness. The government has advised continued surveillance, genome tracking, and public health precautions, especially in states reporting higher transmission rates.
